Hypertension in humans is determined by a dominant autosomal gene, and optical atrophy is caused

Hypertension in humans is determined by a dominant autosomal gene, and optical atrophy is caused by a recessive sex-linked gene. A woman with optic atrophy married a hypertensive man, whose father was also hypertensive and his mother was healthy. 1) What is the probability that a child in this family will suffer from both anomalies (in%)? 2) What is the probability of having a healthy child (in%)?

Solution.
X ° – the presence of atrophy (recessive), X – the absence of atrophy.
A – hypertension
a – no hypertension.
Parent genotypes:
Mother – X ° X ° aa (since she is sick with atrophy and without hypertension)
Father – HUAa (since he is not sick with atrophy and his father was with hypertension, and his mother is healthy).
Let’s make a Punnet lattice.
Answer:
1.25
2. 0 (only 25% of daughters will not have these deficiencies, but they will be carriers of atrophy and without hypertension).