A healthy woman with a second blood group, whose father had a first blood group and suffered from hemophilia

| November 19, 2020 | education

A healthy woman with a second blood group, whose father had a first blood group and suffered from hemophilia, married a healthy man with a fourth blood group. What is the probability of the birth in this family of a son with a third blood group, not a hemophiliac (among all descendants)? Give your answer as a decimal fraction, without rounding.

Hemophilia is a disease linked to the X chromosome, the gene is recessive (h) Therefore healthy (H)
Father of wife: Xh Y ii
Wife: 2 blood group is healthy, if the father has 1 blood group, then she has IA i, and as her father was hemophilic, then genotepically she is heterozygous XHXh
Husband: 4 blood group healthy – XHY IAIB
p: Xh Y ii x XHY IAIB
G: XH IA, Xh IA, XH i, Xh i (x) XH IA, XH IB, Y IA, Y IB
f1: 16 offspring in total, equally m and f
But the boy we only need one (XHY IBi) => 1/16



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