A high content of intercellular substance is characteristic of tissue.

For connective tissue. Connective tissue is the most common and varied type of tissue. It includes fibrous tissue, fat, cartilage, bone, bone marrow, and blood. As the name suggests, connective tissues often bind other organs together, hold the organs in place, soften them, and fill the space.

Connective tissue differs from other types in that extracellular material (matrix) usually takes up more space than cells, and cells are relatively far apart. Fat is an exception with cells that are in close contact with each other; but with large non-living intracellular lipid droplets, the fat contains much more non-living material than living material.