A man suffers from hemophilia, and his parents are healthy on this basis. The woman is healthy and is not

A man suffers from hemophilia, and his parents are healthy on this basis. The woman is healthy and is not a carrier of the hemophilia gene. The hemophilia h gene is located on the sex X chromosome. Determine the genotypes of the parents of the husband, the married couple, as well as the genotypes and phenotypes of the likely offspring.

Let us designate a chromosome in which the recessive gene that causes the development of hemophilia is inherited by descendants as X h. Then the chromosome with the gene that determines the development of the normal blood coagulation system will be designated as X H.

A man with hemophilia has the X h Y genotype. The chromosome Y, which determines the development of his body according to the male type, he received from his father, and the chromosome containing the pathological gene from his mother. A healthy male father is X H Y. A healthy mother must be able to pass on the abnormal gene to the offspring, therefore, she is heterozygous -X H X h.

The woman is healthy and, according to the condition, is not a carrier of the pathological gene. She has a homozygous genotype X H X H and produces eggs of the same type – X H.

A man with hemophilia X h Y produces two types of sperm, X h and Y.

The possible offspring of this married couple will be represented by the following options:

healthy heterozygous girls who are carriers of the pathological gene (X H X h) – 50%;

healthy boys (X H Y) – 50%.