A man with hemophilia (h) and having the first blood group marries a woman with normal blood clotting
A man with hemophilia (h) and having the first blood group marries a woman with normal blood clotting and having a second blood group. The woman is diheterozygous for both of the above signs. Make a scheme for solving the problem. Determine the genotypes of the parents and possible offspring, the probability of having a daughter in this family , a patient with hemophilia with the first blood group.
Man with hemophilia
with the first blood group: I (0) I (0) X (h) Y married to a woman I (A) I (0) X (H) X (h) the second group is healthy, carrier
gametes: I (0) X (h) I (A) X (H) I (A) X (h)
I (0) Y I (0) X (H) I (0) X (h)
Genotypes of possible offspring: I (A) I (0) X (H) X (h) a healthy daughter, a carrier with a second blood group,
I (A) I (0) X (h) X (h) daughter is sick with hemophilia with the second blood group,
I (0) I (0) X (H) X (h) healthy daughter, carrier with first blood group,
I (0) I (0) X (h) X (h) daughter is sick with hemophilia with the first blood group,
I (A) I (0) X (H) Y healthy son, group 2,
I (A) I (0) X (h) Y sick son, second group,
I (0) I (0) X (H) Y healthy son first group,
I (0) I (0) X (h) Y sick son, first group. The probability of having a sick daughter with the first blood group is 12.5%.