A mother who is not a carrier of the hemophilia gene and a father with hemophilia had 2 daughters and 2 sons. determine the genotypes of parents, genotypes and phenotypes of children, if the hemophilia gene is recessive and sex-linked.
It is well known that the inheritance of hemophilia is linked to the X chromosome.
Let’s designate the chromosome carrying the pathological gene as Xg. The mother, according to the condition, is not a carrier of such a gene, therefore she will be recorded as XGXG, her body will produce XG eggs.
The father suffers from the indicated blood coagulation pathology, therefore, he is XgY. His body produces Xg and Y sperm.
All possible offspring of this married couple will be represented by the following options:
healthy girls who are latent carriers of the blood coagulation pathology gene (XGXg) – 50%;
healthy boys (XGY) – 50%.
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