Causes and conditions for protein denaturation?

Protein denaturation involves the destruction of the destruction of both secondary and tertiary structures. Since denaturation reactions are not strong enough to break the bonds between peptides, the primary structure (amino acid sequence) remains unchanged after the denaturation process. Denaturation disrupts the normal alpha and beta helix in the protein and unwinds it into a random shape.
Denaturation occurs due to the violation of the binding interactions responsible for the secondary (hydrogen bond with amides) and tertiary structure.



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