Define the main directions of foreign policy in the middle of the 16th century.

The main directions of the foreign policy of the Russian state in the 16th century were:

1) The conquest of the Astrakhan and Kazan khanates;

2) War with the Crimean Khanate, which constantly threatened the southern regions of the country;

3) The government’s desire to break through to the Baltic Sea, as a result, the Livonian War was unleashed, but, unfortunately, Russia was defeated in it.