Down’s disease is associated with the appearance of an extra 21st pair of chromosomes in the human genotype, therefore, such a change is called ..
This anomaly is explained by the presence of an extra chromosome in the 21st pair, that is, instead of the normal two, another third chromosome appears. This pathological change is called trisomy. The development of patients is accompanied by mental retardation; changes in the external and internal structure of the body are also possible. The appearance of trisomy is associated with nondisjunction of chromosomes during division. To determine a possible abnormality in a child in the early stages of pregnancy, an analysis of the amniotic fluid is taken from the mother and the presence of a protein that is responsible for the development of this disease is determined.
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