Hemophilia is a sex-linked recessive trait. Can a normal man to woman have a hemophilic child?
Hemophilia is a sex-linked recessive trait. Can a normal man to woman have a hemophilic child? Hemophilia is a recessive gene and is located on the X chromosome
Let’s designate the chromosome linked to the hemophilia gene Xh, and the chromosome that determines the development of the normal blood coagulation system will be XH. The Y chromosome, which determines the male phenotype, does not contain alternative information about the blood coagulation system.
A child with hemophilia will be XhY if he is a boy, and XhXh if he is a girl.
A girl with hemophilia cannot be born to a healthy parental couple, since a father who is capable of transmitting a recessive trait would also suffer from her.
A hemophilic boy can arise from a healthy XHY male producing XH and Y sperm and a healthy female heterozygous for the trait in question, XHXh, producing XH and Xh eggs.
Answer: they can.