How does a live vaccine differ from an inactivated one? What is the disadvantage of live vaccines?

With inactivated vaccination, the antigen is inactivated and cannot return to virulence, causing disease. With live vaccination, there is always the possibility that the antigen could revert to virulence and cause disease.

Inactivated immunity takes longer to develop and may be short-lived. Living immunity develops rapidly and may last for a longer period.

The inactivated vaccine is safe. During live vaccination, the temperature should always be observed (4 ° C to 8 ° C). Short periods outside the refrigerator can destroy the antigen. The exception is anthrax, which is in the form of a spore.



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