How does prophase 1 of meiosis differ from prophase of mitosis and why?

The first division of meiosis is identical to mitosis, except that there is an additional phenomenon observed during prophase I – crossing over. In homologous chromosomes (making up a pair), overlap and exchange of chromatid fragments occurs. The result is intrachromosomal mixing of alleles: all genes located on a pair of chromosomes can be welded due to crossing over, which modifies the association of alleles carried by each chromosome. Thus, two chromosomes of each pair after meiosis differ from the two original chromosomes, each of which contains unchanged chromatin and a recombinant.



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