How will the structure of the protein change if the place of the AAA triplet in the DNA
How will the structure of the protein change if the place of the AAA triplet in the DNA molecule is replaced by the AGA triplet?
Protein is synthesized not on DNA, but on the messenger RNA chain. That, in turn, is built along one of the DNA strands according to the complementarity rule.
First, let’s find the mRNA sequences that are encoded in these DNA fragments:
AAA = UUU,
AGA = UCU.
Now, according to the table of the genetic code, we will establish which amino acids are encoded by these codons.
UUU – phenylalanine,
UCU – serine.
As you can see, a completely different peptide will be encoded.
A nucleotide substitution is a point (gene) mutation. In this case, the structure of the protein may not change if the new codon encodes the same amino acid, which is associated with the redundancy of the genetic code.