Hypophosphatemia is inherited as an autosomal recessive trait. What is the probability of having children

Hypophosphatemia is inherited as an autosomal recessive trait. What is the probability of having children in a family where one of the parents is heterozygous and the other is homozygous for this trait?

Let us designate the gene for hypophosphatemia by the letter “a” (small, since this gene is recessive by the condition of the problem).

Then the genotype of the father will look like “aa”, and the genotype of the heterozygous mother as “Aa”.

Mother’s gametes: A and a.

Father’s gametes: a.

Variants of the genotypes of the offspring: Aa and aa.

1: 1.

Answer: the probability of the birth of children with hypophosphatemia in this family, as well as the probability of the birth of healthy children, is 50%.



One of the components of a person's success in our time is receiving modern high-quality education, mastering the knowledge, skills and abilities necessary for life in society. A person today needs to study almost all his life, mastering everything new and new, acquiring the necessary professional qualities.