Near which city did the Romans suffer the most significant defeat?

This was the city of Cannes. In 218 BC, the army of Hannibal and the 90 thousandth army of the Romans met here. The Romans here relied on superiority in the infantry. But the outstanding mind of Hannibal gave him the opportunity to use the power of the enemy against him. Thus, at the end of the battle, the Roman legions were surrounded and utterly defeated. This was a great disaster for Rome, which actually brought him one step away from death. But still Rome managed to escape.