One of the forms of cystinuria (metabolic disorder of four amino acids) is inherited as an autosomal

One of the forms of cystinuria (metabolic disorder of four amino acids) is inherited as an autosomal recessive trait. however, in heterozygotes, only an increased content of cystine in the urine is observed, and in homozygotes, the formation of cystine stones in the kidneys. determine the possible forms of manifestation of cystinuria in children in a family where one of the spouses suffered from this disease, and the other had only an increased content of cystine in the urine.

c – cystinuria, C – norm. Heterozygotes have an increased content of cystine in the urine, while homozygotes develop cystine stones.

Parents: cc × Cc

Gametes: c – C c

Offspring: Cc have an increased content of cystine in the urine, cc formation of kidney stones (1: 1).