Suppose that Werner’s syndrome (pre-aging of a person) is inherited as a recessive trait. What is the prognosis

Suppose that Werner’s syndrome (pre-aging of a person) is inherited as a recessive trait. What is the prognosis for the appearance of this syndrome in offspring if it is known that the wife is healthy, but her father had Werner’s syndrome? The husband is also healthy, but his mother grew old early.

Let’s designate the syndrome as “a”. The genotype of his wife is Aa (since she is healthy, but her father had the syndrome). The genotype of the husband is Aa (since he is healthy, but his father grew old early). Possible types of gametes of wife A a, possible types of gametes of father A a. Possible genotypes and phenotypes of their children: AA (healthy), Aa (healthy, carrier of the syndrome), Aa (healthy, carrier of the syndrome), aa (sick).



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