The name of the protein that forms the centriole.

Tubulin is the main building block of microtubules that make up centrioles. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagella movement, and in the cytoskeleton. Tubulin is a heterodimer that consists of a-tubulin and b-tubulin; both subunits have significant homology. The most studied tubulins were isolated from vertebrates. Microtubules can be viewed in immunofluorescence microscopy, which allows one to observe the intracellular organization of proteins in the form of a supramolecular structure.



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