What are chromosomal mutations? Examples

Chromosomal mutations are those that lead to a change in the number, size and organization of chromosomes. There are 2 types of such mutations: 1) intrachromosomal and 2) interchromosomal.
Intrachromosomal includes: 1) duplication (doubling), 2) deletion (loss of the inner portion of the chromosome), 3) inversion (rotation of a portion of the chromosome by 180 degrees).
Interchromosomal includes: 1) reciprocal – interchange of sections of non-homologous chromosomes, 2) transpositions – sections of chromosomes change position or are part of other chromosomes, 3) dicentric and polycentric – the union of 2 or more parts of non-homologous chromosomes, 4) centric – when 2 centromeres are combined non-homologous acrocentric chromosomes.



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