What is the merit of E. Jenner and L. Pasteur in the invention of the vaccine?

In 1796, Edward Jenner used a substance obtained from the blister of a smallpox patient to develop immunity in a boy. The patient survived and gained immunity. Thus began almost two centuries of struggle against smallpox. A century later, Louis Pasteur invented vaccination. Formally, it was used earlier, by the same Jenner, but Pasteur began to use weakened or dead viruses to develop immunity. It was these two people who made a huge contribution to medicine. Now smallpox has been completely defeated by humanity, and many viruses do not pose a threat to us thanks to vaccinations.