What is the probability of having children with two anomalies in a family where one parent suffers from cataracts

What is the probability of having children with two anomalies in a family where one parent suffers from cataracts and is deaf-mute, and the other spouse is healthy, but heterozygous for the cataract gene?

Obviously, this task implies that deaf-dumbness and cataracts are recessive signs.

Let’s designate the gene that causes the development of cataracts in humans as k, then the gene that causes the development of a healthy lens of the eye will be K.

Let’s designate the gene that causes the development of deaf-dumbness as l, then the gene that leads to the development of normal hearing will be L.

A deaf-mute parent with cataract will be a digomozygote for recessive genes – kkll. It will produce kl germ cells and transmit only pathological genes to the offspring.

A healthy, but heterozygous parent for the cataract gene will be recorded as KkLL, and it will produce two types of germ cells – KL and kL.

The offspring of this married couple will look like this:

healthy children with pathological genes (KkLl) – 50%

children with normal hearing and speech, suffering from cataracts (kkLl) – 50%.

Answer: the probability of having children with the two anomalies under consideration in this family is 0%.



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