When and how did the Byzantine Empire fall?

The Byzantine Empire undermined its strength and power in the confrontation with Persia, and then with the young Arab state. Having lost most of the lands, Byzantium was far from the powerful state that it was in the early Middle Ages. In 1204, during the Crusade, the crusaders took and plundered the crusaders. However, this finally undermined the strength of the state. Gradually, Turkish tribes and state formations began to put pressure on him. And so it went on until the Ottoman Empire captured Constantinople in 1453.